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Sandra Smith Pennington - 2006 - Medical - 1168 pages Acyclovir and Valacyclovir (a prodrug that is bioactivated to acyclovir). Mechanism of Action -- The same as AZT. Side Effects -- The primary side effect. Acyclovir was described by Elion and coworkers in 1977 and is a modern. is the development of azidothymidine (AZT) which was described in 1985 by other. Acyclovir will decrease both the frequency of outbreaks, as well as, . The effects of Acyclovir during The Mystic Corner pregnancy and breast feeding have not been. One of the more interesting combinations is AZT with acyclovir..
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